Substance fraction (subst.fr.)

Substance fraction

Synonyms

Mole fraction, amount-of-substance fraction

Abbreviation

Subst.fr.

Definition in words

Amount-of-substance of component B divided by amount-of-substance of system 1

Definition by equation

Systematic terms

Substance fraction of component B in system 1
Ratio scale
  • Value sets are positive numerical values
  • Algebraic operations are allowed (a=nb; a≠nb)
Numerical values from 0-∞

Unit

10-18, 10-15, 10-12, 10-9, 10-6, 10-3, 1 (one), etc.

Unit, one (1) is omitted in the NPU syntax

Non-recommended term

Amount fraction, number fraction

Reference

Ferard G, Dybkaer R, Fuentes-Arderiu X. Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences : Recommendations 2016. 1 ed: Royal Society of Chemistry; 2016. 182 p. doi:10.1039/9781782622451.

 

Laboratory field

Examples

Clinical Chemistry

 

Example 1
Generic abbreviated
NPU27300 Haemoglobin beta chain(B)—N-(1-deoxyfructos-1-yl)haemoglobin beta chain; subst.fr. = ? mmol/mol
Abbreviated  result NPU27300 Haemoglobin beta chain(Blood)—N-(1-deoxyfructos-1-yl)haemoglobin beta chain; substance fraction = 48 millimol per mol
Full result NPU27300 Haemoglobin beta chain(B)—N-(1-deoxyfructos-1-yl)haemoglobin beta chain; subst.fr. = 48 mmol/mol
Written expression The substance fraction of N-(1-deoxyfructos-1-yl)haemoglobin beta chain of all Haemoglobin beta chain in Mr. Smith’s blood is [48] mmol/mol.
Equation

 Notes

Trivial name for this measurement description is HbA1c

Generally, for any fraction or ratio the units are numerical values, however, due to IFCC recommendations, “mmol/mol” was selected as unit for this measurement only.

Nordin, International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) IFCC Scientific Division, Committee on Nomenclature, Properties and Units (C-NPU): Gunnar and René Dybkær. 2007. Recommendation for term and measurement unit for “HbA1c”. Clinical Chemical Laboratory Medicine. 45(8): 1081-1082. Retrieved 30 Aug. 2019, from doi:10.1515/CCLM.2007.245 

Clinical Microbiology

Example 2
Generic abbreviated
NPU54252 Rubellavirus antibody(P; IgM)—Rubellavirus antibody(IgM; high avidity); subst.fr.(proc.) = ?
Full result NPU54252 Rubellavirus antibody(Plasma; Immunoglobulin M)—Rubellavirus antibody(Immunoglobulin M; high avidity); substance fraction(procedure) = 0.3 x one
Abbreviated result NPU54252 Rubellavirus antibody(P; IgM)—Rubellavirus antibody(IgM; high avidity); subst.fr.(proc.) = 0.3
Written expression The substance fraction of Rubellavirus-antibody (IgM) with high avidity of all Rubellavirus-antibody (IgM) in Mr. Smith’s plasma is [0.3].The measurement is performed according to a procedure defined by the laboratory.
Equation

Molecular Biology and Genetics

Example 3
Generic abbreviated
NPU54270 JAK2 gene(DNA; Marrow)—JAK2 gene(LRG_612: g.93526G>T); subst.fr. = ?
Full result NPU54270 JAK2 gene(DNA; Marrow)—JAK2 gene(LRG_612: g.93526G>T); substance fraction(procedure) = 0.7 x one
Abbreviated result NPU54270 JAK2 gene(DNA; Marrow)—JAK2 gene(LRG_612: g.93526G>T); subst.fr. = 0.7
Written expression The substance fraction of the variant, LRG_612: g.93526G>T in the JAK2 gene, of all JAK2 gene (DNA) in Mr. Smith’s marrow is [0.7].
Equation

Thrombosis and Haemostasis

Example 4
Generic abbreviated
NPU28671 Von Willebrand factor(P)—Von Willebrand factor(vWA1); subst.fr. = ?
Full result NPU28671 Von Willebrand factor(Plasma)—Von Willebrand factor(vWA1); substance fraction = 0.05 x one
Abbreviated result NPU28671 Von Willebrand factor(P)—Von Willebrand factor(vWA1); subst.fr. = 0.05
Written expression The substance fraction of Von Willebrand factor(vWA1) of all Von Willebrand factor in Mr. Smith’s plasma is [0.05].
Equation

Reference

NPU database, https://www.ifcc.org/ifcc-scientific-division/sd-committees/c-npu/npusearch/ and http://www.labterm.dk/default.aspx

 

  • Kind-of-property

    • Nominal kind-of-property

    • Kind-of-quantity

      • Unitary kind-of-quantity

        • Rational unitary kind-of-quantity

          • Substance fraction

Reference

  • Dybkaer R. Concept system on ‘quantity’: formation and terminology. Accredit Qual Assur. 2013;18(3):253-60.
  • Dybkaer R. ISO terminological analysis of the VIM3 concepts ‘quantity’ and ‘kind-of-quantity’. Metrologia. 2010;47(3):127-34.
Date Term Note
1996-01-01 Substance fraction Term established